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Keyword:isotope ratio analysis

Japanese Team Develops High-Temperature, High-Pressure Isotope Ratio Analysis Method for Tracing Halogenated Pollutants

Japanese Team Develops High-Temperature, High-Pressure Isotope Ratio Analysis Method for Tracing Halogenated Pollutants

Researchers from Shibaura Institute of Technology (SIT) and the National Institute of Advanced Industrial Science and Technology (AIST) in Japan have collaboratively developed a customized high-temperature, high-pressure combustion interface for liquid chromatography-isotope ratio mass spectrometry (LC-IRMS), enabling carbon stable isotope ratio (δ¹³C) analysis of various halogenated organic compounds. The research findings were published online on August 2, 2026, and will appear in Volume 1421 of Analytica Chimica Acta, scheduled for release on November 1, 2026. Source of the new high-temperature, high-pressure LC-IRMS system: Professor Hiroto Kawashima, SIT, Japan. Halogenated organic compounds are widely present in disinfection byproducts, pesticides, refrigerants, and industrial chemicals, some of which exhibit persistence, bioaccumulation, and toxicity. Traditional environmental monitoring primarily relies on concentration measurements, which makes it difficult to directly provide information on pollutant sources and environmental transformation processes. δ¹³C analysis can offer clues for studying chemical sources, production processes, and environmental fate, but organic pollutants containing strong carbon—chlorine or carbon—fluorine bonds are difficult to fully oxidize under conventional LC-IRMS combustion conditions, limiting the application of this technique.

2026-09-02

Thermo Fisher Scientific Launches First Orbitrap Mass Spectrometers for Isotope Ratio Analysis

Thermo Fisher Scientific Launches First Orbitrap Mass Spectrometers for Isotope Ratio Analysis

Thermo Fisher Scientific recently launched the Thermo Scientific Orbitrap Isora mass spectrometer and Orbitrap Isora Pro mass spectrometer in Waltham, Massachusetts, USA. The company stated that these are its first Orbitrap instruments equipped with a dedicated isotope ratio analysis mode. The two mass spectrometers launched this time will form an integrated workflow together with the Thermo Scientific Vanquish Duo ultra-high performance liquid chromatography system and the new Isotope Discoverer software, providing molecular-level isotope ratio analysis capabilities to laboratories and researchers worldwide. Isotope ratio analysis can help researchers determine the source of compounds and their formation processes by measuring natural variations in isotopes within samples, helping...

2026-08-26

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